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Attachment Inhibitor project.in Parma, Italy, and again in 2024 for a. Pfizer API manufacturing plant.
These projects were significantly different in form, conception and function, but common threads in the design and delivery approach helped both to achieve success and industry recognition.. Pfizer API, Singapore: efficiency and value.This new API (active pharmaceutical ingredient) manufacturing plant is a flagship facility for Pfizer’s regional network, a $1bn SGD investment covering almost 430,000 square feet and delivered entirely during the COVID-19 pandemic.The facility needed to represent best practice in GMP (good manufacturing practice) and digital automation while remaining cost effective to build and operate.. Bryden Wood was engaged to review and optimise a previously developed concept design for the site’s dry processing (milling and sieving) building.
We worked closely with client stakeholders to analyse the root process requirements, identify over-provisions in the proposed design, and consolidate production onto less equipment.. Capturing these root requirements in 3D digital models called.“Chips” (sets of interacting components.
allowed us to rapidly evaluate a wide range of configuration options with client stakeholders engaged every step of the way..
The reduced equipment requirements allowed us to pivot away from the originally proposed central spine corridor towards a simpler configuration of process rooms with perimeter circulation on both sides.The aims of efficiency, intensification, recycling and waste reduction, if applied correctly, are directly shared with improving today’s economics.
In an arena where regulation and taxation will be aligned to carbon reduction, there is also a strategic necessity for long-term profitability.Framing the drivers in this way would chime much more favourably with shareholders, boardrooms, and in the political arena.. Economics are certainly the key driver in the generics manufacturers who operate in price-sensitive markets.
Accounting for as high as 90% of prescription drugs, their strategies and business decisions have huge influence on the impact of the sector.They often do not carry the overhead of strategic teams, and there is an opportunity to share, promote and assist their move towards more efficient use of solvents through the sharing of insights and examples.